Journal of Osseointegration https://www.journalofosseointegration.eu/jo <h1>Journal of Osseointegration</h1> <p>The aim of the<strong> Journal of Osseointegration</strong> in the Implant Dentistry field is to publish high quality contemporary, timely, innovative, interesting and clinically relevant information that will be used for improvement of the care of our patients. The rapid growth of research and more application of advanced clinical procedures has led us to start this new journey, that we hope will be a journey of success. The objective of all the people involved in this project will be to present the data in an accurate, fair and unbiased way. Each paper will be given the close attention that it merits and only manuscripts with well designed projects, conducted in a manner that follows sound scientific principles will be accepted. Also the rapidity of the reviewing process will be a key goal, this will be ensured by a web based submission and colse supervision on the reviewing process. A concerted effort will be made to shorten the time between submission, correction, acceptance of the manuscript, online publication, and print publication. We aim also for a high standard of technical editing, which serves to ensure the consistency of the content style and the fact that the language should be as unambiguous and clear as possible. The help of all involved people will be of outstanding relevance in achieving this mission.</p> Ariesdue srl, Milan, Italy. Online version powered by PAGEPress Scientific Publications, Pavia, Italy en-US Journal of Osseointegration 2036-4121 <p>The<strong> Journal of Osseointegration</strong> has chosen to apply the&nbsp;<a href="http://creativecommons.org/licenses/by-nc/4.0/" target="_blank" rel="noopener"><strong>Creative Commons Attribution NonCommercial 4.0 International License</strong></a>&nbsp;(CC BY-NC 4.0) to all manuscripts to be published.</p> Incidence, association and treatments of maxillary sinus diseases due to odontogenic causes: retrospective clinical study https://www.journalofosseointegration.eu/jo/article/view/657 <p style="font-weight: 400;"><strong>Aim:</strong>This retrospective study aimed to assess the incidence of dental procedures causing maxillary sinus diseases, investigate possible associations between types of dental procedures and maxillary sinus involvement, and describe treatment details for maxillary sinus diseases due to odontogenic causes.</p> <p style="font-weight: 400;"><strong>Materials and Methods:</strong> The study was conducted at San Raffaele Hospital, Milan, Italy, and included 51 patients (24 males, 27 females, average age 56 years) who developed maxillary sinus infections following dental procedures. Data collection involved clinical histories and radiographic examinations, with diagnoses confirmed by intra-oral X-rays, orthopantomography, and Cone Beam CT. The study focused on patients who developed infections involving the maxillary sinus after dental procedures performed in the maxillary region.</p> <p style="font-weight: 400;"><strong>Results:</strong> Results indicated that dental implant placement was most frequently associated with maxillary sinus diseases (39.2%), followed by tooth extraction (17.6%), carious pathology (13.7%), endodontic procedures (11.8%), disodontiasis (9.8%), and sinus floor elevation surgery (7.8%). Surgical treatment was prevalent (86.3%), with trans-nasal, trans-oral, and combined approaches. Chi-square tests showed significant associations between dental procedures and maxillary sinus diseases (χ² = 32.14, p &lt; 0.05) and between disease types and treatment modalities (χ² = 18.29, p &lt; 0.05). ANOVA indicated age-related differences in disease severity and treatment choice (F(2, 48) = 4.73, p &lt; 0.05). Logistic regression and correlation analyses identified age, gender, and dental procedure type as significant risk factors.</p> <p style="font-weight: 400;"><strong>Conclusion: </strong>The findings underscore the importance of early diagnosis and multidisciplinary management to prevent complications associated with maxillary sinus diseases due to odontogenic causes. Further clinical studies are necessary to confirm these results and improve management strategies.</p> B. D'orto G. Polli S. Giuntoli M. Nagni Copyright (c) 2024 Tecniche Nuove spa http://creativecommons.org/licenses/by-nc/4.0 2024-06-24 2024-06-24 16 2 140 148 10.23805/JO.2024.657 Unraveling the Anti-Staining Properties of Dental Resin Cements: a Study with a Newly Developed Universal Resin Cement https://www.journalofosseointegration.eu/jo/article/view/655 <p><strong>Aim </strong>This study examines the anti-staining properties of newly developed and existing dual-cure resin cements for prosthetic dental applications.</p> <p><strong>Materials and Methods </strong>To replicate a common inlay restoration, a CAD/CAM inlay was machine-milled from dima Hybrid Resin Blank Plus (Kulzer Japan) for a class II cavity abutment tooth made of i-TFC Core Resin (Sun Medical). The inlay and abutment tooth were then cemented using the new universal resin cement (Kulzer Japan ZEN™ Universal Cement) and five existing resin cements (3M RelyX™ Universal Resin Cement, 3M RelyX™ Unicem 2, Ivoclar Vivadent SpeedCem<sup>®</sup> Plus, GC G-CEM ONE™ EM, and Kuraray Noritake Panavia™ SA Cement Universal). Subsequently, the specimens underwent a 24-hour immersion in red wine at 37°C, after which they were sectioned to evaluate the degree of internal staining. Recognizing that degree of monomer conversion, water sorption and water solubility are potential influencing factors, these properties of each cement were measured and compared with their respective staining tendencies. In addition, the amount of stain compounds was quantified by a new test protocol.</p> <p><strong>Results </strong>There was a moderate correlation (R<sup>2</sup> = 0.60) between the degree of color change and water solubility, suggesting that the leaching of water-soluble components in resin cement may contribute to red wine staining. In addition, there was a strong correlation (R<sup>2</sup> = 0.94) between the amount of stain compounds and the degree of color change, indicating that the extent of staining can be effec-tively elucidated by a straightforward physical model, without requiring the consideration of intricate chemical interactions between stain molecules and resin composition.<br /><br /><strong>Conclusions</strong></p> <p>Within the limitations of this study, it can be concluded that the use of low-water-soluble and anti-staining resin cements, such as the newly developed ZEN<sup>TM</sup> Universal Resin Cement, has considerable advantages in aesthetic dentistry.</p> <p> </p> Y. Yamada C. Akino Y. Kamimoto Copyright (c) 2024 Tecniche Nuove spa http://creativecommons.org/licenses/by-nc/4.0 2024-06-26 2024-06-26 16 2 130 139 10.23805/JO.2024.655 Techniques for retrieving the fractured abutment screws in screw-or cementretained implant-supported prostheses. A systematic review https://www.journalofosseointegration.eu/jo/article/view/643 <p><strong>Aim</strong> In implant dentistry, broken abutment screws in implant-supported prostheses constitute a difficult problem that demands exact retrieval methods for effective management. This systematic review intends to evaluate several extraction techniques for fractured abutment screws, with a focus on technology integration, retention method implications, heat management, and efficient abutment screw fracture categorization.</p> <p><strong>Material and methods </strong>This systematic review encompassed a comprehensive analysis of various methodologies employed for fractured abutment screw retrieval in both screwand cement-retained implant-supported prostheses, integrating studies from 2010 to October 2023. To conduct the search, relevant keywords and controlled vocabulary were used in databases including PubMed, Scopus, Web of Science, Google Scholar, and Cochrane. With terms like "Abutment Screw", "Dental Implant Screw", “Fractured Abutment Screw,” and “Abutment Screw Retrieval,” the search was limited to papers published between 2010 and October 2023 to ensure thorough coverage. 18 studies were reviewed, and a total of 86 publications were initially found.</p> <p><strong>Results </strong>The review uncovered developments in the integration of technology, consequences of retention procedures, efficient heat management tactics, specialized therapeutic treatments, preservation methods, and non-invasive retrieval techniques.</p> <p><strong>Conclusions</strong> For fractured abutment screw retrieval to be successful in implant dentistry, innovative technology, cautious retention technique selection, and good heat management strategies, among other factors, are essential. The conclusions highlight the necessity for accuracy, flexibility, and patient-centred treatment while also highlighting the significance of continued research to improve patient outcomes.</p> S. Banerjee T. N. Banerjee A. Debnath P. Paul Copyright (c) 2024 Tecniche Nuove spa http://creativecommons.org/licenses/by-nc/4.0 2024-06-21 2024-06-21 16 2 121 129 10.23805/JO.2024.643 Influence of periodontitis on injectable platelet rich fibrin levels of beta-defensin-1 in periodontal/peri-implant therapy https://www.journalofosseointegration.eu/jo/article/view/642 <p style="font-weight: 400;"><strong>Aim &amp; Background</strong> Periodontitis is an inflammatory condition initiated by polymicrobial flora but mediated by host immune response. This local inflammatory response is further shown to bring about alterations in the expression of various cytokines and proteins at systemic level. Injectable-platelet rich fibrin (i-PRF) which is a derivative of centrifuged blood is widely used in periodontal and peri-implant therapy. It exhibits its anti-inflammatory effect through various proteins especially beta defensin. This study aims to evaluate the influence of periodontitis on human beta-defensin-1 (hBD-1) levels in i-PRF.</p> <p style="font-weight: 400;"><strong>Methods</strong> This case-control study evaluated 50 subjects 25 each in case (periodontitis) group and control (healthy) group for their periodontal status and i-PRF levels of beta defensin (hBD-1).</p> <p style="font-weight: 400;"><strong>Results</strong> There was significantly decreased i-PRF levels of hBD-1 in the periodontitis group compared to the healthy group. The correlation analysis showed there was a relationship between probing depth and hBD-1 levels.</p> <p style="font-weight: 400;"><strong>Conclusion</strong> Thus, it can be concluded that periodontal health status influences the iPRF levels of beta defensin, which can further influence the clinical outcomes of iPRF applications in wound healing and regeneration. Clinical Significance: iPRF from periodontally diseased subjects might have a reduced level of antiinflammatory cytokines (hBD-1) thereby predisposing to a compromised or incomplete healing potential at the site of application.</p> M. Thamaraiselvan R. Pradeep Copyright (c) 2024 Tecniche Nuove spa http://creativecommons.org/licenses/by-nc/4.0 2024-06-24 2024-06-24 16 2 114 120 10.23805/JO.2024.642