State of the art of autologous platelet concentrates in dentistry: A narrative review

Background Over the past 10 years, PRP and PRF have been widely used in dentistry, due to their growth factors and regenerative potentials and have expanded their use in many procedures with results that are now clinically and statistically significant. The initially described procedures included oral surgery, in general, from simple to complex extractions of included third molars. Today their use goes from periodontics to hard and soft tissue regenerative surgery, through oral wound healing up to implant therapy. The aim of this review is to evaluate the state of the art of autologous platelet concentrates in different branches of dentistry. Materials and methods A literature research was conducted through major scientific database without any restriction. Because of the large number of articles included and the wide range of methods and results among the studies found, it was not possible to report the results in the form of a systematic review or meta-analysis. Therefore, a narrative review was conducted.
Results We obtained 2236 results, of which 1621 were published in the last 10 years. After the screening of titles and abstracts, non-topic entries were excluded, 323 reviews and systematic reviews were included, of which 320 passed the English language filter.
Conclusions This review highlights the present state of the art of the use of autologous platelet concentrates in dentistry. According to several recent studies, there is an effective benefit in several clinical outcomes described in using prp or prf in different procedures, while in others further clinical studies are needed.