Biodegradation of three different collagen membranes: A histological study


Submitted: 14 June 2017
Accepted: 14 June 2017
Published: 30 November 2016
Abstract Views: 917
PDF: 3588
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Authors

  • A. Olaechea Division of Implantology, Department of Stomatology, School of Dentistry, Cientifica del Sur University, Lima, Peru.
  • G. Mendoza-Azpur Division of Periodontics, Department of Stomatology, School of Dentistry, Cientifica del Sur University, Lima, Peru.
  • E. Valdivia Division of Periodontics, Department of Stomatology, School of Dentistry, Cientifica del Sur University, Lima, Peru.
  • G. Rasperini Department of Biomedical, Surgical and Dental Sciences, University of Milan, Foundation IRCCS Ca€™ Granda Polyclinic, Milan, Italy.
Aim The aim of this study was to evaluate in vivo the absorption rate of three membranes: bovine collagen (GenDerm, Baumer, Brazil), collagen (Genoss, Dentium, Korea) and porcine dermis membrane (Kytinon M.O.R., Asmopul, Argentina). The additional aims were to evaluate blood vessel penetration and fiber collagen penetration in the early wound healing process. Materials and Methods Four dogs were used for the study and the membranes were applied by subperiosteal placement and analyzed after 15, 30, 60 and 90 days. Results The absorption rate of 65% absorption. This bovine collagen membrane was completely absorbed after 90 days. At this time point absorption of the bovine collagen (Collagen®, Dentium, Korea) was >65%, while absorption of the porcine dermis (Kytinon®, Asmopul, Argentina) was found to be between just 35% and 65%. Conclusion Blood vessel penetration and fiber collagen penetration in the three membranes showed significant differences, with faster vascularization and collagen penetration in the more rapidly absorbed membranes.

Supporting Agencies


Olaechea, A., Mendoza-Azpur, G., Valdivia, E., & Rasperini, G. (2016). Biodegradation of three different collagen membranes: A histological study. Journal of Osseointegration, 8(2), 15–19. https://doi.org/10.23805/jo.2016.08.02.01

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