A qualitative and quantitative assessment of bone regeneration after sinus augmentation. A randomized comparative study

Abstract

Aim Bone augmentation in the atrophic maxilla is a prerequisite for successful implant rehabilitation. The aim of this study is to evaluate regeneration of bone and to compare the efficacy of PRF in bone regeneration following sinus augmentation surgery in the edentulous posterior maxilla. 

Materials and methods A prospective randomized comparative study was conducted at our institution. The study was allocated into 3 groups: Group I, Platelet Rich Fibrin (PRF) as a stand-alone agent; Group II, Autogenous bone graft; Group III, Alloplastic bone graft (Tricalcium phosphate putty). Groups II and III received PRF as an adjuvant. 

Results On comparing the post-operative bone height and radiodensity of the augmented region, there was statistical significance in Groups II and III. A 6 month post operative CBCT reveals a better bone regeneration in Group III (Alloplastic bone graft – β-Tricalcium phosphate putty). 

Conclusions The results of this study suggest that both autogenous and alloplastic bone grafts are viable graft materials for maxillary sinus augmentation. Platelet rich fibrin, when used as an adjuvant to either alloplastic or autogenous graft enhances bone formation by delivering growth factors at the site of regeneration. However, as a stand-alone agent it failed to provide radiographic evidence of bone formation. The posterior maxilla has always been the most challenging site for implant rehabilitation. There have been various studies, comparing different grafts for successful bone regeneration and stability after implant rehabilitation. Our study aims to search for an ideal grafting material in the maxillary sinus region.

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Author Biographies

Vivek Narayanan, Department of Oral and Maxillofacial Surgery, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu, India

Dean, Professor and HOD, Department of Oral and Maxillofacial surgery, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu – 603203

Saravanan Chandran, Department of Oral and Maxillofacial Surgery, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu, India

Professor, Department of Oral and Maxillofacial surgery, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu – 603203

Karthik Ramakrishnan, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu – 603203

Associate Professor, Department of Oral and Maxillofacial surgery, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu – 603203

Abinaya Subramanian, Department of Oral and Maxillofacial Surgery, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu, India

Assistant Professor, Department of Oral and Maxillofacial surgery, SRM Kattankulathur Dental College and Hospital, Chennai, Tamil Nadu – 603203

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Published
2021-04-01
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Keywords:
Alloplastic, Autogenous, Maxillary sinus lift, Platelet rich fibrin, Bone Regeneration
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How to Cite
Arumugam, K., Narayanan, V., Chandran, S., Ramakrishnan, K., & Subramanian, A. (2021). A qualitative and quantitative assessment of bone regeneration after sinus augmentation. A randomized comparative study. Journal of Osseointegration, 13(1), 13-20. https://doi.org/10.23805/JO.2020.13.01.3